Google is Using Old Books and New Technology to Combat Disease
- by Michael Stillman
A recent story on the Google Research blog quickly caught my eye: Using new technology and old books to combat disease. We tend to think of old books as a source of information about the past, which they certainly are, but the headline indicated the people at Google Brain were using them to solve today's major problems.
The issue they were tackling concerned insect-borne diseases. Mosquitoes and ticks spread dangerous diseases such as malaria and lyme disease. Add to that how annoying the itching bites can be and there is good reason to seek new ways to repel these pests. The most common repellent for mosquitoes, the active ingredient in many of the repellents you find in the store, is Deet (technically, N,N-diethyl-meta-toluamide). It was discovered 80 years ago after extensive government research. However, it does have certain drawbacks, such as damaging some types of fabrics, not working with all pests, and possibly some negative effects on people.
What the Google researchers discovered was the government had carried on extensive testing in the 1940s when they selected Deet, but what they tested and what were the results was virtually impossible to find. It was stashed away in various places with no practical way to locate it all. However, these were Google researchers and they were aware that Google had scanned and preserved reams of this old stuff as part of Google Books. This allowed them to locate these old reports and review them. What they found was surprising. The government had tested thousands of potential repellents.
Exactly how Google Brain used all this data is beyond the scope of this article, which is another way of saying the computer functions and science are beyond my understanding. The computers are using AI (Artificial Intelligence) to do comparisons of promising molecules to find others that may be useful. Eventually, they came up with a list of 10 molecules that may be more effective than Deet. Further testing will be needed. Hopefully, they will find better repellents that will save lives in areas plagued by disease-bearing insects while making our picnics more pleasant.
The issue for us is old books, and the application of new technology to them. Google Books now has 40 million volumes scanned into their database. This is definitely the information age and that is a lot of data. The issue now is making connections, using the existing data to learn things no one realized was there, and applying it to questions we want to answer today. That is where AI comes in. It can “think” at computer speed, not human speed, and it can sort through voluminous amounts of data in split seconds. Perhaps you've had a chance to ask questions of, or even get stories or poems written on demand for you by ChatGPT. Maybe you have created some unique images through Stable Diffusion. What they can do with AI and data is astonishing, at least to those of us who grew up in the age of pencils and paper. They are fun to play around with, but as Google Brain is proving, AI is serious business. Combine it with data from old books and other sources, and there is no telling what you may discover.
In our own case, over the past 20 years we have put together a database of over 12.5 million records from auctions and other sources pertaining to sales of old books. It has enabled us to not only find descriptions and prices from the past, but to create a scale for estimating the current value of old prices based on an index generated strictly from book sales. We recently developed a method of using the database to estimate the value of entire collections, not just one book at a time. We can estimate how frequently a particular title is likely to come up at auction in the future. We can determine how frequently certain words are used in descriptions of a particular title. Still, there is much more to be learned, not only about books but about the interests of people at various times, and which changes predict our interests in the future. As long as the data has been accumulated, AI will enable us to learn much more than we ever dreamed possible. These are exciting times.
Sotheby’s Shelf Life: Books, Manuscripts and Works on Paper from the Library of Stanley J. Seeger and Christopher Cone 25 June – July 7
Sotheby’s, July 7: Ludwig van Beethoven. Autograph sketches for the overture "Die Weihe des Hauses", op.124, [1822], UNPUBLISHED. £150,000 to £200,000.
Sotheby’s, July 7: Jane Austen. Pride and Prejudice, 1813, first edition, 3 volumes, contemporary half calf. £50,000 to £70,000.
Sotheby’s, July 7: Walt Whitman. Leaves of Grass, Brooklyn, 1855, first edition, first issue, original green cloth, the Doheny copy. £50,000 to £70,000.
Sotheby’s, July 7: Binding—Sangorski & Sutcliffe—Omar Khayyam. Rubaiyat, London, 1872, third edition, in a magnificent jewelled Peacock binding. £15,000 to £20,000.
Sotheby’s, July 7: George Eliot. Middlemarch, Edinburgh and London, 1871, first edition in the original parts. £20,000 to £30,000.
Forum Auctions The Private Library: Fine Printing & Private Press books, the collection of the late David Chambers July 9, 2026
Forum, July 9: Hassall (Joan) A large collection of over 300 original woodblocks of engravings for various books, v.d., with Hassall's engraver's glass water-globe (Qty) - Est. £10,000-15,000
Forum, July 9: Eragny Press.- [Bradley (Katherine Harris) & Edith Emma Cooper], "Michael Field." Whym Chow, Flame of Love, one of only 27 copies, inscribed by Bradley, the rarest book from the press, 1914. - Est. £3,000-4,000
Forum, July 9: [Moore (Thomas Sturge)] [Wood Engravings], 71 wood-engravings printed by David Chambers from the original blocks, the only set on Japanese Hosho paper, from an edition of 5 sets, [1970]. - Est. £3,000-4,000
Forum Auctions The Private Library: Fine Printing & Private Press books, the collection of the late David Chambers July 9, 2026
Forum, July 9: La Fontaine (Jean de) Contes et Nouvelles en vers, 2 vol., engraved plates after Eisen, fine early 19th century blue morocco, gilt, by Bradel l'ainé, Amsterdam [Paris], 1762. - Est. £2,000-3,000
Forum, July 9: Erotica.- Prostitution.- Pretty Women of Paris (The); Their Names and Addresses, Qualities and Faults..., [Paris], privately printed at the Press of the Prefecture de Police, 1883. - Est. £3,000-4,000
Forum, July 9: Vale Press.- Ricketts (Charles) & Lucien Pissarro. De la Typographie et de l'Harmonie de la Page Imprimée…, [one of 216 copies], bound in dark blue morocco tooled in gilt, by Sarah T.Prideaux, 1898. - Est. £1,000-1,500
Forum Auctions The Private Library: Fine Printing & Private Press books, the collection of the late David Chambers July 9, 2026
Forum, July 9: Martin (John) Illustrations of the Bible, complete set of 20 mezzotints, good impressions, rarely found in early states, [c.1831-1835]. - Est. £1,000-1,500
Forum, July 9: Golden Cockerel Press.- Four Gospels of the Lord Jesus Christ (The), one of 500 copies, Mary Gill's copy, Waltham St. Lawrence, 1931 with a signed proof of engraving on japon numbered 10/10 (2) - Est. £5,000-7,000
Forum, July 9: Boccaccio (Giovanni) The Decameron, 3 vol., vol.1 extra-illustrated by John Buckland Wright with c.150 erotic original drawings in pen & ink and pencil, 1886 [extra-illustrated c.1940]. - Est. £10,000-15,000
Forum Auctions The Private Library: Fine Printing & Private Press books, the collection of the late David Chambers July 9, 2026
Forum, July 9: Cox (Morris) Collection of Gogmagog Press Books, 35 vol., rare complete collection of printed books issued by the press, limited editions, most signed by Cox, 1957-83. - Est. £10,000-15,000
Forum, July 9: Wynkyn de Worde.- [Terentius Afer (Publius)] [Comedie...], [Paris, Josse Badius: sold in London by Wynkyn de Worde, & others], [15 July 1504]. - Est. £4,000-6,000
Forum, July 9: Mosley (James) Ornamented Types. Twenty-Three Alphabets from the Foundry of Louis John Pouchée, 2 vol., one of 10 copies for presentation, from an edition of 210, 1992-93. - Est. £1,000-2,000
Forum Auctions The 10th Anniversary Sale Fine Books, Manuscripts and Works on Paper July 16, 2026
Forum, July 16: Inundation papyrus. P.Michael 4, the ‘Inundation papyrus’, a geographical account of the Nile near Canopus, in Greek, remains of two columns from a manuscript scroll on papyrus, Egypt, second century CE. £12,000-18,000
Forum, July 16: Book of Hours, use of Sarum, manuscript on vellum, 6 full-page miniatures, with famous Middle English inscriptions, Southern Netherlands for the English market, [c.1430]. £30,000-50,000
Forum, July 16: Qu'ran, Arabic manuscript on burnished, stencilled, and gold-flecked paper, 447ff., Sultanate Gujarat, Ahmadabad, [after 1411 but no later than 1442]. £15,000-20,000
Forum Auctions The 10th Anniversary Sale Fine Books, Manuscripts and Works on Paper July 16, 2026
Forum, July 16: Turner (William). A New boke of the natures and properties of all wines that are commonly vsed here in England, rare first edition of the first English book on wine, By William Seres, 1568. £20,000-£30,000
Forum, July 16: Spenser (Edmund). The Faerie Queene. first edition, Printed [by John Wolfe] for William Ponsonbie, 1590. £30,000-40,000
Forum, July 16: Shakespeare (William). The Comedie of Errors, extracted from the first folio, Isaac Jaggard and Edward Blount, 1623. £15,000-20,000
Forum Auctions The 10th Anniversary Sale Fine Books, Manuscripts and Works on Paper July 16, 2026
Forum, July 16: Fleming (Ian). Casino Royale, first edition, signed presentation inscription from the author, 1953. £40,000-60,000
Forum, July 16: d'Agoty (Jacques-Fabien Gautier). Anatomie de la Tête, first edition, Paris, chez le Sieur Gautier, 1748. £10,000-15,000
Forum, July 16: Martial Arts.- Lee (Bruce). 'Praying Mantis style' Kung Fu book, containing numerous annotations, diagrams and graphs in Bruce Lee's hand, c. 1960. £50,000-70,000
Forum Auctions The 10th Anniversary Sale Fine Books, Manuscripts and Works on Paper July 16, 2026
Forum, July 16: Warre (Capt. Henry James). Sketches in North America and the Oregon Territory, first edition, rare hand-coloured issue, 1848. £30,000-40,000
Forum, July 16: Norie (John William). The Marine Atlas, or Seaman's Complete Pilot for all the principal places in the known world..., 1826. £30,000-50,000
Forum, July 16: Mao Tse-tung.- Kim Il-sung.-[Note book for visitors from China to Korea], signed by Mao and Kim, [Beijing, 1954]. £10,000-15,000