Rare Book Monthly

Articles - February - 2023 Issue

Google is Using Old Books and New Technology to Combat Disease

A recent story on the Google Research blog quickly caught my eye: Using new technology and old books to combat disease. We tend to think of old books as a source of information about the past, which they certainly are, but the headline indicated the people at Google Brain were using them to solve today's major problems.

 

The issue they were tackling concerned insect-borne diseases. Mosquitoes and ticks spread dangerous diseases such as malaria and lyme disease. Add to that how annoying the itching bites can be and there is good reason to seek new ways to repel these pests. The most common repellent for mosquitoes, the active ingredient in many of the repellents you find in the store, is Deet (technically, N,N-diethyl-meta-toluamide). It was discovered 80 years ago after extensive government research. However, it does have certain drawbacks, such as damaging some types of fabrics, not working with all pests, and possibly some negative effects on people.

 

What the Google researchers discovered was the government had carried on extensive testing in the 1940s when they selected Deet, but what they tested and what were the results was virtually impossible to find. It was stashed away in various places with no practical way to locate it all. However, these were Google researchers and they were aware that Google had scanned and preserved reams of this old stuff as part of Google Books. This allowed them to locate these old reports and review them. What they found was surprising. The government had tested thousands of potential repellents.

 

Exactly how Google Brain used all this data is beyond the scope of this article, which is another way of saying the computer functions and science are beyond my understanding. The computers are using AI (Artificial Intelligence) to do comparisons of promising molecules to find others that may be useful. Eventually, they came up with a list of 10 molecules that may be more effective than Deet. Further testing will be needed. Hopefully, they will find better repellents that will save lives in areas plagued by disease-bearing insects while making our picnics more pleasant.

 

The issue for us is old books, and the application of new technology to them. Google Books now has 40 million volumes scanned into their database. This is definitely the information age and that is a lot of data. The issue now is making connections, using the existing data to learn things no one realized was there, and applying it to questions we want to answer today. That is where AI comes in. It can “think” at computer speed, not human speed, and it can sort through voluminous amounts of data in split seconds. Perhaps you've had a chance to ask questions of, or even get stories or poems written on demand for you by ChatGPT. Maybe you have created some unique images through Stable Diffusion. What they can do with AI and data is astonishing, at least to those of us who grew up in the age of pencils and paper. They are fun to play around with, but as Google Brain is proving, AI is serious business. Combine it with data from old books and other sources, and there is no telling what you may discover.

 

In our own case, over the past 20 years we have put together a database of over 12.5 million records from auctions and other sources pertaining to sales of old books. It has enabled us to not only find descriptions and prices from the past, but to create a scale for estimating the current value of old prices based on an index generated strictly from book sales. We recently developed a method of using the database to estimate the value of entire collections, not just one book at a time. We can estimate how frequently a particular title is likely to come up at auction in the future. We can determine how frequently certain words are used in descriptions of a particular title. Still, there is much more to be learned, not only about books but about the interests of people at various times, and which changes predict our interests in the future. As long as the data has been accumulated, AI will enable us to learn much more than we ever dreamed possible. These are exciting times.

Rare Book Monthly

  • Sotheby’s
    Fine Manuscript and Printed Americana
    27 January 2026
    Sotheby’s, Jan. 27: An extraordinary pair of books from George Washington’s field library, marking the conjunction of Robert Rogers, George Washington, and Henry Knox. $1,200,000 to $1,800,000.
    Sotheby’s, Jan. 27: An extraordinary letter marking the conjunction of George Washington, the Marquis de Lafayette, and Benjamin Franklin. $1,000,000 to $1,500,000.
    Sotheby’s, Jan. 27: Virginia House of Delegates. The genesis of the Declaration of Independence and the Bill of Rights. $350,000 to $500,000.
    Sotheby’s
    Fine Manuscript and Printed Americana
    27 January 2026
    Sotheby’s, Jan. 27: (Gettysburg). “Genl. Doubleday has taken charge of the battle”: Autograph witness to the first day of the Battle of Gettysburg, illustrated by fourteen maps and plans. $200,000 to $300,000.
    Sotheby’s, Jan. 27: President Lincoln thanks a schoolboy on behalf of "all the children of the nation for his efforts to ensure "that this war shall be successful, and the Union be maintained and perpetuated." $200,000 to $300,000.
    Sotheby’s, Jan. 27: [World War II]. An archive of maps and files documenting the allied campaign in Europe, from the early stages of planning for D-Day and Operation Overlord, to Germany’s surrender. $200,000 to $300,000.
  • Forum Auctions
    Fine Books, Manuscripts and Works on Paper
    29th January 2026
    Forum, Jan. 29: Plato. [Apanta ta tou Platonos. Omnia Platonis opera], 2 parts in 2 vol., editio princeps of Plato's works in the original Greek, Venice, House of Aldus, 1513. £8,000-12,000
    Forum, Jan. 29: Book of Hours, Use of Rome, In Latin, illuminated manuscript on vellum, [Southern Netherlands (probably Bruges), c.1460]. £6,000-8,000
    Forum, Jan. 29: Correspondence and documents by or addressed to the first four Viscounts Molesworth and members of their families, letters and manuscripts, 1690-1783. £10,000-15,000
    Forum Auctions
    Fine Books, Manuscripts and Works on Paper
    29th January 2026
    Forum, Jan. 29: Shakespeare (William). The Dramatic Works, 9 vol., John and Josiah Boydell, 1802. £5,000-7,000
    Forum, Jan. 29: Joyce (James). Ulysses, first edition, one of 750 copies on handmade paper, Paris, Shakespeare and Company, 1922 £8,000-12,000
    Forum, Jan. 29: Powell (Anthony). [A Dance to the Music of Time], 12 vol., first editions, each with a signed presentation inscription from the author to Osbert Lancaster, 1951-75. £6,000-8,000
    Forum Auctions
    Fine Books, Manuscripts and Works on Paper
    29th January 2026
    Forum, Jan. 29: Chaucer (Geoffrey). Troilus and Criseyde, one of 225 copies on handmade paper, wood-engravings by Eric Gill, Waltham St.Lawrence, 1927. £3,000-4,000
    Forum, Jan. 29: Borges (Jorge Luis). Luna de Enfrente, first edition, one of 300 copies, presentation copy signed by the author to Leopoldo Marechal, Buenos Aires, Editorial Proa, 1925. £3,000-4,000
    Forum, Jan. 29: Nolli (Giovanni Battista). Nuova Pianta di Roma, Rome, 1748. £6,000-8,000
    Forum Auctions
    Fine Books, Manuscripts and Works on Paper
    29th January 2026
    Forum, Jan. 29: Roberts (David). The Holy Land, Syria, Idumea, Arabia, Egypt, & Nubia, 3 vol., first edition, 1842-49. £15,000-20,000
    Forum, Jan. 29: Blacker (William). Catechism of Fly Making, Angling and Dyeing, Published by the author, 1843. £3,000-4,000
    Forum, Jan. 29: Herschel (Sir John F. W.) Collection of 69 offprints, extracts and separate publications by Herschel, bound for his son, William James Herschel, 3 vol., [1813-50]. £15,000-20,000

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